bristol myers squibbSomerville, MA
Principal Scientist, Translational Computational Biology
Principal Scientist, Translational Computational Biology
Principal Scientist, Translational Computational Biology
bristol myers squibbSomerville, MA
yesterday
Research and Development in BiotechnologyResearch and Development in the Physical, Engineering, and Life SciencesBiological Product Manufacturing
Apply for this role (opens in a new tab)Principal Scientist, Translational Computational Biology within BMS's Oncology Translational IPS team, focusing on embedding computational expertise into oncology drug development from discovery through early clinical phases. Responsibilitiesanalyze multimodal patient-derived datasets-including spatial transcriptomics, spatial proteomics, RNA-seq, WES, ctDNA, TCR-seq, and flow cytometry
support biomarker and patient stratification strategies
interpret data to inform target validation, IND-enabling studies, and early clinical decisions
develop and deploy AI-enabled methods for evidence integration and hypothesis generation
lead computational ownership of spatial biology platforms
mentor junior scientists and enhance portfolio capabilities through scalable, reproducible workflows
Requirements:
Ph. D. in computational biology, bioinformatics, or related, with 4+ years relevant experience, or equivalent with additional years
strong programming skills in R/Python
experience with spatial biology platforms (Xenium, Visium, COMET, PhenoCycler)
familiarity with oncology drug development and biomarker strategies
proven ability to translate complex data into actionable insights
Preferredexpertise in spatial transcriptomics and proteomics, AI and machine learning applications in translational science, perturbation biology, and regulatory network analysis
experience in oncology translational research or early clinical development
publication record in methods development
High-Value Oncology, spatial biology, multimodal patient data, early-phase clinical support, biomarker strategy, and computational innovation in drug discovery.
Work SetupLikely hybrid or onsite in Cambridge, with collaboration across multi-disciplinary teams.
Also on the board Same function, level within a rung
Level
Lead
Location
Somerville, MA
Occupation
Bioinformatics Scientists
Industry
Research and Development in Biotechnology
Posted
yesterday